Deprogel-PGS (Pregelatinized Starch)

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Deprogel-PGS (Pregelatinized Starch)

Pregelatinised Starch

Compliance I.P, USP/NF, B.P., E.P., J.P.
Usage Binder & Disintegrant
Packing 60kg H.D.P.E Drums
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Deprogel-PGS (Pregelatinized Starch)

Pregelatinized Starch Manufacturer

DEPROGEL-PGS is a unique excipient that serves a dual purpose as both a binder and a disintegrant. It is a partially pregelatinised starch modified strictly by physical methods, ensuring no chemical residues.

This product is highly stable, heat-treated for longevity, and offers exceptional flowability, making it the ideal choice for modern tablet and capsule manufacturing processes.

  • Direct Compression: Excellent flow properties allow for direct compression without additional glidants.
  • Versatile Application: Suitable for Wet Granulation and Roller Compaction as well.
  • Binder & Disintegrant: Acts as a mild binder while ensuring effective disintegration.
  • High Stability: Long shelf life due to specialized physical modification and heat treatment.

Technical Specifications (IP/USP)

Parameter Specification
Description White to off-white powder; odorless.
Solubility Swells in cold water; practically insoluble in organic solvents.
pH 4.5 – 7.0
Loss on Drying Not more than 14.0%
Iron Not more than 20 ppm
Oxidizing Substances Negative (Complies with IP/USP)
Sulphated Ash Not more than 0.6%

* Standard pharmacological specifications. Actual batch COA available on request.

Often Asked Questions

Technical insights about utilizing Pregelatinized Starch in your formulations.

What is Pregelatinized Starch used for in Pharma?

Pregelatinized Starch is a multi-functional excipient used as a binder, disintegrant, and flow aid. It acts as a tablet binder in wet granulation and direct compression, increasing tablet hardness while still allowing for disintegration.

Is Deprogel-PGS suitable for Direct Compression?

Yes, Deprogel-PGS is specifically processed to have excellent flow properties, making it an ideal choice for direct compression formulations where flowability is critical.

How does Pregelatinized Starch differ from normal starch?

Pregelatinized Starch has been physically modified (cooked and dried) to become cold-water swellable. This gives it better binding and flow properties compared to native starch.

What standards does Deprogel-PGS meet?

Deprogel-PGS complies with the pharmacopoeial standards of IP, USP/NF, and BP, ensuring high quality and consistency for pharmaceutical use.